Spine Surgery - Auxin Surgery

Indications

Revision spine surgery

Easy & safe detachment of fibrosis adhering to the dura mater, implanted devices and peripheral nerves, tendons & muscles

Preserve targeted structures (e.g. of a risk of iatrogenic lesions) and so, will lead to better intraoperative and perioperative outcomes

Resources

Revision spine surgery case with CADISS® - Dr. Collard, 2020

Dr. Xavier Collard. Head of Orthopaedic department. Internship supervisor & Master of Medicine Education – ULB – CHU Ambroisé Paré, Belgium

Spine revision case with CADISS® - Dr. triffaux, 2021

Dr. Michel Triffaux. Neurosurgeon, head of department. Centre Hospitalier de Wallonie Picarde. Tournai. Belgium

Dr. X. Collard, BELGIUM (CHU Ambroise Paré. 2018-2020 & Pr. O. De Witte, BELGIUM (ULB Erasme) & Dr. A. Lubansu, BELGIUM (ULB Erasme)

Use of CADISS® medical devices to facilitate dissection of epidural fibrosis in patients who undergo a revision in spine surgery after at least one year.

Dr. Xavier Collard. Head of Orthopaedic department. Internship supervisor & Master of Medicine Education – ULB – CHU Ambroisé Paré, Belgium.

Pr. Olivier De Witte. Head of Neurosurgery department – Hospital ULB Erasme, Belgium.

Dr. Alphone Lubansu, Assistant clinical head, Neurosurgeon – Hospital ULB Erasme, Belgium.

Objective : The primary objective of the study is to evaluate the ability of the CADISS® System to dissect epidural fibrosis in spine revision surgery after at least one year without cutting.

The secondary objectives cover the surgeon satisfaction and the usability the CADISS® System. The safety of the device is evaluated on the reported AE

Methodology : This study is a prospective, multi-sites, open label, single cohort clinical trial evaluating the use of CADISS® medical devices to facilitate dissection of epidural fibrosis in patients who undergo a revision in spine surgery after at least one year. Number of patients: 21. Three visits are planned in the course of the study: a screening (V1)/pre-surgical visit (V1bis), the intervention day (V2), a post-operative follow-up at 4 to 5 days following the surgery (V3) and a follow-up visit at 6 weeks post-surgery.

Conclusion : Globally the results of this study confirm the conclusions of the prospective randomized trial performed by Denaro in 2008 The safety, usability, and effectiveness of the CADISS® system in lumbar spine revision is confirmed. The usability and ergonomics of the CADISS® System in both the manual and remote – control configurations were verified. It was concluded that the device is safe and effective for its intended clinical use.

Denaro V & al. 2008

Denaro V, Di Martino A, Longo UG, Costa V, Papalia R, Forriol F, Denaro L. Effectiveness of a mucolytic agent as a local adjuvant in revision lumbar spine surgery. Eur Spine J 2008; 17:1752-1756

Casale M & al. 2010

Casale M, Di Martino A, Salvinelli F, Trombetta M, Denaro V. Mesna for chemically assisted tissue dissection. Expert Opin Investig Drugs 2010;19(6): 699-707.

CADISS®, a new solution for more selective dissection in spine & MS surgeries, BELGIUM (17/12/2020)

Lecturer : Dr. Xavier Collard. Head of Orthopaedic department. Internship supervisor & Master of Medicine Education – ULB – CHU Ambroisé Paré, Belgium.

Moderator : Pr. Frederic Schuind. Head of Orthopaedic and Traumatology department. Ordinary Professor at the ULB – Erasme University Hospital, Belgium.

SUMMARY
CADISS®, a new solution for more selective dissection in spine & MS surgeries, BELGIUM (17/12/2020)

Lecturer : Dr. Xavier Collard. Head of Orthopaedic department. Internship supervisor & Master of Medicine Education – ULB – CHU Ambroisé Paré, Belgium.

Moderator : Pr. Frederic Schuind. Head of Orthopaedic and Traumatology department. Ordinary Professor at the ULB – Erasme University Hospital, Belgium.

EXPERIENCE OF THE USE OF CADISS®(15/12/2021)

Lecturer : Dr. Michel Triffaux, neurosurgery, spine unit. CHWAPI Belgium.7500 Tournai.

Moderator : Valérie Gordenne, Chief Scientific Officer, AuXin Surgery

Dr. Xavier Collard

CHU Ambroise Paré, Spine Surgery. Mons, Belgium

« Patients who undergo for spine revision surgery with epidural fibrosis in which CADISS® is used intraoperatively present better intraoperative and perioperative parameters. The surgical difficulty and the incidence of dural tears and intraoperative bleeding from epidural veins are significantly reduced. »

Dr. Michel Triffaux

Neurosurgeon, head of department, internship supervisor. (Centre Hospitalier de Wallonie PicardeCHR Citadelle). Tournai, Belgium

« At first I was septic but after using the CADISS it really helps in spinal revision surgery which is always a challenge for the surgeon. »